Production Company: Warner Bros.
Producers: Zak Penn, Dennis Edwards
Directors: Piet Kroon, Tom Sito (live action by the Farelly brothers)
Screenwriter: Marc Hyman
Domestic Release Date: August 10th, 2001
Cast:

Osmosis Jones: Ricardo Curtis / Chris Rock
Drixorial: Richard Bazley / David Hyde Pierce
Thrax: Duncan Marjoribanks / Lawrence Fishburne
The Chief: Dean Wellins / Joel Silver
Mayor: Dave Brewster / William Shatner
Leah: Wendy Purdue / Brandy
Mayor's opponent: / Ron Howard
Frank: Bill Murray

Awards:

• Annie Awards:
  • Annie nomination for Outstanding Achievement in an Animated Theatrical Feature.
  • Annie nomination for Outstanding Individual Achievement for Character Animation (Dean Wellins).
  • Annie nomination for Outstanding Individual Achievement for Effects Animation.
  • Annie nomination for Outstanding Individual Achievement for Voice Acting by a Male Performer in an Animated Feature Production (William Shatner).
  • Outstanding Individual Achievement for Writing in an Animated Feature Production.

Comments:

Osmosis Jones is Warner Bros. Feature Animation's 3rd completely animated release after Quest For Camelot and The Iron Giant. The film is a comedy/adventure about a street smart white blood-cell called Osmosis Jones who teams up with a rookie cold tablet to fight a virus that is attacking their host body, a construction worker named Frank Detomello.

Trailer: